The workhorse binder-filler for a custom formulation. Excellent compressibility and a neutral taste — the usual backbone of a direct-compression excipient system, and the largest single ingredient by weight in most formulas.
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MCC binds under pressure without a separate granulation step, doing double duty as both filler and binder in a direct-compression formula.
Doesn't interfere with the taste of chewable or fast-dissolving formats — a pharmaceutical-grade filler that's also common in food and nutraceutical tablets.
Most direct-compression formulas start with MCC at 60–75% of the excipient system, before the active ingredient and the other three roles are added.
Confirm performance for your specific formulation with your own testing before a production run.
| Spec | Value |
|---|---|
| Appearance | White, free-flowing powder |
| Role | Binder / filler |
| Physical state | Solid |
| Directly compressible | Yes |
| Typical use rate | 60–75% of the excipient blend (before active ingredient) |
| Approx. mesh size | 100–200 mesh |
| Storage | Room temperature, sealed container |
| Bag sizes | 1 kg, 2 kg, 5 kg |
| Bulk sizes | 500 kg, 1 ton, 2 ton, 5 ton pallet lots |
As a diluent and binder in direct-compression formulations — it adds bulk to reach a workable tablet weight and holds the compressed powder together under pressure, doing both jobs at once.
60–75% of the excipient blend (before adding your active ingredient) is a typical starting point. See our guide on building a direct-compression blend from scratch for the full ratio breakdown.
Not for most formulations — MCC alone has no lubricant or glidant, so tablets are likely to stick in the die and the powder may not flow evenly into the die cavity. Pair it with magnesium stearate and silicon dioxide, or use a pre-balanced blend like ReadyBlend.
4.7 out of 5, based on 3 reviews.
Our go-to binder/filler — consistent compressibility batch to batch.
Good starting point for building a blend from scratch, exactly as described.
Solid workhorse excipient. Mesh size matched what we needed for our formulation.